Background: Palliative care aims to promote quality of life and relieve suffering for patients at the end of life. Nurses play a central role in this care, where they are responsible for medical interventions and provide emotional support. The work is often challenging and places high demands on the nurse's competence and ability to meet the needs of patients and their families. Aim: This study aimed to explore nurses’ experiences of palliative care. Method: A general literature review was conducted according to Friberg’s (2022) steps for a descriptive approach. Ten scientific articles including both qualitative and quantitative, were reviewed and summarized based on similarities and differences in the findings Results: Three main themes were identified: communication in palliative care, moral distress and suffering in palliative care, and competence development for nurses. Moral stress and emotional challenges refer to ethical dilemmas, feelings of inadequacy and the need for support. The need for support and competence development highlights further education, supervision and interprofessional collaboration as important factors to manage the demands of care. Conclusion: Nurses experience palliative care as meaningful but demanding. To provide good care, they need access to education, supervision and clear guidelines. Keywords: Communication, competence development, general literature review, moral stress, nurses, palliative care.