This research explores the success factors of the research-based process for creating high-performing innovation teams, called the CIT-process. This chapter is part of a study through which problems in the implementation of high-performing innovation teams were identified when being used by innovation management practitioners (practitioners). The CIT-process is a five-step process prior to the innovation process. Before organizations were involved, practitioners at an innovation management firm were educated in the CIT-process and evaluated. Three innovation teams were created by the practitioners, conducting real innovation projects, facilitated by the practitioners. Data were collected through filed notes and interviews with the participants and the practitioners. Three main themes appeared as key success factors: knowledge adoption, knowledge transition, and knowledge transfer. Limitations are highlighted and future research is suggested.