Background: Palliative care is provided to terminally ill patients, with diseases that are incurable, to alleviate patients' suffering. In the end-of-life phase, both patients and relatives have expressed a need for physical and psychological care from nurses. A holistic approach to care, viewing the individual as a unique being with body, soul, and spirit, is something that patients and relatives desire nurses to consider. Aim: The study aimed to explore nurses' experiences of caring for patients in palliative care at the end of life. Method: The chosen method is a general literature review, analyzing ten qualitative and two quantitative articles. Results: Three themes were identified: The importance of good palliative care, The importance of communication in palliative care and The importance of time and knowledge. Conclusion: Nurses view caring in palliative care at the end of life as meaningful; however, barriers such as time constraints, lack of knowledge, and high workloads affect their ability to meet patients' physical, psychological, social, and existential needs. Effective communication and collaboration are essential for providing good, person-centered care that alleviates suffering in patients receiving palliative care at the end of life. Keywords: Caring, End of life, Experiences, General literature review, Nurses, Palliative care.