The aim is to investigate what challenges preschool staff may face when they put preschool inclusion into practice and to locate, present and synthesise recommended evidence-based ways of overcoming these challenges. Eight focus group interviews with preschool staff members from the same number of preschool units were conducted to identify the challenges. In addition, scoping reviews were carried out. The focus group interviews revealed ten challenges. Three examples are to support children's communication, to monitor and evaluate preschool inclusion and to decrease the need and implementation of segregated support and therapy. The reviews come up with possible ways to overcome these challenges. At a time when inclusion is a right, an international statement and a worldwide Goal, the results form the basis for interesting discussions, and professional development, which may enable the creation of preschools that are inclusive from the very beginning and encourage important improvement efforts in practice.