This paper describes a comparison between two measurement systems for medical endurance test for rodents, a new running wheel system and an old system named ADEA. The ADEA test chamber system has been criticized because it is cumbersome and involves a lot of manual work which therefore limits the number of test cells that can be run simultaneously. Comparison between the systems has been done via measurements of dopamine levels and thereafter calculating correlation factor. The running wheel system has shown to provide at least as good physical strain as the well tested ADEA system.